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Kalamazoo College Student Newspaper (2018)
(Kalamazoo, Mich. : Kalamazoo College, 2018)Three issues of the student newspaper The Index from the 2018 Winter Quarter are included. To obtain permission to reproduce, please contact the Kalamazoo College Archives at archives@kzoo.edu. -
Leukocyte Recruitment into the CNS is Mediated via Microglia-Dependent Signaling Following Neurotropic Herpesvirus Infection
(Kalamazoo College, 2018)Neurotropic viruses are diverse and can establish lifelong and lethal infections in the brain, inducing encephalitis and contributing to severe neurodegeneration. However, the mechanisms through which microglia, the brain's ... -
Molecular Characterization and Susceptibility Testing of Extended Spectrum P- Lactamase (ESBL) Producing Enterobacteriaceae
(Kalamazoo College, 2018)Extended Spectrum p-lactamases (ESBLs) are produced by Escherichia coli and Klebsiella pneumoniae. ESBLs are enzymes that bind and hydrolyze p-lactam antibiotics, rendering the enzymes ineffective. The p-lactamases identified ... -
The Dynamics of Fitness and Metagenomic Trajectories in a Long-Term Evolution Experiment with E. coli
(Kalamazoo College, 2017)During evolution in a constant environment, large asexual populations undergo an initial phase of rapid fitness increase, followed by an indefinitely long period of slower adaptation. While the initial phase has been ... -
The Effect of Rare and Novel Temperature Regimes on the Release of Cryptic Variation in the Fathead Minnow, Pimephales promelas
(Kalamazoo College, 2018)Warmer temperatures brought about by climate change will have widespread effects on the physiology and life history of organisms. Importantly, populations will be increasingly exposed to novel environmental conditions. ... -
Variation in Foraging Preferences by Bumble Bees Through Time with a Focus on Bombus affinis Conservation
(Kalamazoo College, 2018)Bumblebees (Bombus spp.) provide valuable pollination services to both wild Plant communities and crops. Given the decline of some bumble bee species and the recent placement of the rusty patched bumble bee (Bombus affinis) ... -
BKM120, a Novel PI3K Inhibitor, Promotes Medulloblastoma Cell Death Through the Prevention of Akt Phosphorylation and Activation of Apoptotic Pathways.
(Kalamazoo College, 2015)Medulloblastoma is the most common malignant pediatric brain tumor, and is fatal in 30% of cases. Traditional treatment of medulloblastoma consists of surgical resection followed by chemotherapy and radiation. However, for ... -
Effects of Cladophora glomerata on Terrestrial Shoreline Plant Communities
(Kalamazoo College, 2015)Cladophora glomerata is a filamentous green macroalga native to marine and freshwater ecosystems, which can be found as floating mats or as loose masses on soft substrates. A recent increase in incidence of C. glomerata ... -
A Novel 3D Culture Model to Study TSP2 Proteolysis
(Kalamazoo College, 2014)The extracellular matrix (ECM) gives bone its strength and integrity and provides discrete structural and biological contributions to bone form and function. The Thrombospondin protein family is comprised of five secreted ... -
Generation of Knockout Cell Lines for the Invasion-regulating Scaffold Gene AFAPILI in Sarcoma Cells by CRISPR/Cas9 Technology
(Kalamazoo College, 2015)There are over fifty types of sarcomas known in the world today. However, in most cases, the molecular mechanisms which cause their poor prognoses are still a mystery. Cancer metastasis is one of the most unifying ... -
Whole Brain Irradiation and its Effects on Spatial Memory in Fisher-344 Rats
(Kalamazoo College, 2015)The idea of synaptic plasticity is that the connection of each synapse within a neural network can constantly change due to various factors that can either strengthen or weaken it. The genes that underlie the stabilization ... -
Retinal Ganglion Cell Apoptosis is Mediated Through Activation of a7 Nicotinic Acetylcholine Receptors by PNU-282987 and DMP-543 in in-vivo Models of Glaucoma
(Kalamazoo College, 2015)Glaucoma is a degenerative retinal disease characterized by loss of vision due to the death of retinal ganglion cells (RGCs) in the eyes of mammals. This is primarily caused by buildup of intraocular pressure (IOP) in the ... -
Immunohistochemical Localization and Function of INF2 in the Placenta for Birth Timing
(Kalamazoo College, 2015)Preterm birth (PTB) in humans is classified as birth before 37 weeks of gestation. PTB is a serious health problem as it is the leading cause of death among infants. Overall, PTB is a poorly understood condition that ... -
Immunoproteasome Inhibition Confers Protective Effects in a Murine Model of Adenovirus Myocarditis
(Kalamazoo College, 2015)Myocarditis is an inflammatory disorder that affects the myocardium, or the muscle tissue of the heart. Myocarditis is commonly caused by viral infection, and adenoviruses are frequently identified in patients with ... -
Early Cellular Changes Related to Overproduction of Alzheimer's Amyloid-p Alter Synchronized Network Activity in Computational Model of Hippocampal Theta Rhythm Generation
(Kalamazoo College, 2015)Hippocampal network dysfunction is thought to be an important component of early Alzheimer's disease (AD). Understanding hippocampal network dysfunction can lead to better understanding of the time course and progression ... -
An RT-PCR Approach for Multiple Population Sequencing of Csk in Gasterosteus aculeatus
(Kalamazoo College, 2015)The understanding of local adaptation and its genetics basis are crucial for the study of adaptive radiation and evolutionary biology as a whole. Local adaptation is significantly shaped by organisms' physical environment, ... -
Relative Effects of Climate and Competition on the Annual Growth ofPinus contorta var. latifolia, Pinus ponderosa var. scopulorum, and Pseudotsuga menziesii var. glauca
(Kalamazoo College, 2014)The role of climate and competition in determining species growth is unclear despite the existence of a large body of research. Forest ecology studies report different findings depending on focal species and study site ... -
Co-housing of Mice Leads to Compositional Homogenization of Microbibta Between 7 and 21 Days
(Kalamazoo College, 2015)The mammalian gut is inhabited by a dense population of microbes, including bacteria, which have been shown to play an important role in host health and immunity. The population of these microbes, known as the microbiome, ... -
The Implications of Forest Edge on Northern Goshawk Nest Location in the Bridger-Teton National Forest
(Kalamazoo College, 2013)In the past few decades, scientists have become concerned about declining Northern Goshawk (Accipiter gentilis) numbers and have subsequently focused on identifying and defining characteristics of their nesting habitat ... -
Goldilocks and the Three Shells : When the Home is Just Right for the Hermit Crab Pagurus granosimanus
(Kalamazoo College, 2013)Hermit crabs use gastropod shells as temporary homes. These shells protect their vulnerable, uncalcified abdomens from predation and competing crabs. Previous studies have shown that a lack of adequate housing significantly ...
