Altered Eicosanoid Metabolism Associates with the Salutatory Changes of Salt Restriction in Chronic Kidney Disease
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Authors
Petroff, Julia N.
Issue Date
2019
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
Chronic Kidney Disease (CKD) is a global health crisis
affecting 11 to 13% of people worldwide. It often coincides with the
development of hypertension, making hypertension a critical predictor
of CKD progression. Hypertension is generally linked to increased
salt intake and can be treated with antihypertensive drugs and/or a salt
restricted diet (SRD). However, antihypertensive medications don’t
work in patients with salt sensitivity, which means their only treatment
option is a salt restricted diet. Diagnosis of salt sensitivity takes time,
since the current method of identification is inconvenient and tedious.
As more hypertensive patients have become salt sensitive, the
necessity of a simpler, more effective identification method has
increased. Current studies are focusing on finding potential
biomarkers of salt sensitivity, but little is done in patients with CKD.
Our study aimed to identify potential eicosanoid metabolites as salt
sensitivity biomarkers in CKD patients by studying their
concentration changes in response to SRD.
Description
1 Broadside. 48"W x 36"H
Citation
Publisher
Kalamazoo, Mich. : Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.