β-glycyrrhetinic acid alters expression and phosphorylation of the gap junction protein connexin-43 in enterocyte-like cells
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Authors
Becker, Russell E.
Issue Date
2009
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
• Connexin protein monomers complex to
form gap junction intercellular channels
between various communicating cell types
Connexin-43 is the major connexin expressed in intestinal epithelial cells in culture (R.B. & M.K., unpublished)
β-glycyrrhetinic acid is a chemical inhibitor of gap junction communication in these and other cell types, with unknown mode of action
Blocking gap junctions in intestinal epithelial cells also blocks the epithelial healing process (R.B. & M.K., unpublished)
Description
1 broadside
Citation
Publisher
Kalamazoo, Mich. : Kalamazoo College.
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.