Differential loop analysis of phenotypically and genetically juxtaposed mouse strains using visualization tools
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Authors
Carr, Eleanor
Issue Date
2023
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
Biological Framework: Previous study suggests promoters are key to gene regulation, can be regulated from far away. Mice strains C57BL/6 (BLK6) and DBA/2J (DBA) have differential gene expression in fear and anxiety genes. Experiments to isolate these differences, however, are laborious time-consuming.
Computational Framework: Hi-C data and single-cell data modalities all describe differential expression in slightly different ways. Data collected using Hi-C bulk and single-cell sequencing.
Goals: Simultaneous visualization of all modalities. Classifier for future gene assessment.
Description
1 Broadside. 36"W x 42"H
Citation
Publisher
Kalamazoo, Mich. : Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.