Design and Synthesis of 7-Hydroxy-2-(2-phenylethyl)chromones as Non-Nitrogenous 5-HT2 Receptor Ligands

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Authors
Chang, Rachel S.
Issue Date
2018
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en_US
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Abstract
Chromones are non-amine natural compounds. Identified by benzoannelated y-pyrone core. Name originates from Greek word chroma, which means color. 2-(2-phenylethyl) chromones (2-PEC,2) were first isolated in1978. 2-PECs have shown activity as neuroprotectants and antimicrobials. 7-hydroxy-2-(2-phenylethyl)chromone (7-HPEC,3) is an attractive canidate as a serotonin receptor ligand.
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Kalamazoo, Mich. : Kalamazoo College
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