Neurotensin-1 receptor agonist PD149163 interacts with N-methyl-D-aspartate receptor antagonist MK-801 and the effects on working memory

dc.contributor.authorDesjarlais, Lynette
dc.date.accessioned2015-05-12T15:41:28Z
dc.date.available2015-05-12T15:41:28Z
dc.date.issued2015
dc.description1 Broadside. Designed using Microsoft PowerPoint. 48"W x 36"Hen_US
dc.description.abstractA novel molecule, neurotensin-1 agonist PD149163 targets both the limbic system and dopaminergic areas to increase neurotensin levels, which may play a critical role in the pathogenesis of schizophrenia. A rat model testing working memory utilizing a Barnes maze found that PD149163, when interacting with MK-801, an NMDA receptor antagonist, did not improve induced memory deficits, yet increased induced velocity deficits.en_US
dc.description.sponsorshipKalamazoo College. Department of Biology. Diebold Symposium, 2015en_US
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10920/29636
dc.language.isoen_USen_US
dc.publisherKalamazoo, Mich. : Kalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Diebold Symposium Presentation Collectionen
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.en
dc.titleNeurotensin-1 receptor agonist PD149163 interacts with N-methyl-D-aspartate receptor antagonist MK-801 and the effects on working memoryen_US
dc.typePresentationen_US
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