Exploring Ubiquitination in Cancer Regulation
Loading...
Authors
Hernandez, Jennefer
Issue Date
2023
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
Ubiquitylation is a post-translational modification that controls many highly regulated, biological processes that are vital to maintaining cell homeostasis (Duan & Pagano et al., 2021). Ubiquitylation is involved in protein degradation, altering kinase activity, and interfering with protein interactions and dysregulation of the ubiquitin system has been associated with the initiation and development of cancer (Mansour., 2018; Duan & Pagano et al., 2021). In this study, we will focus on the role of DCAF15, an E3 ubiquitin protein, and its role in the promotion of pro-pathogenic pathways that lead to the development of Acute Myeloid Leukemia also known as AML.
Description
1 Broadside. 48"W x 36"H
Citation
Publisher
Kalamazoo, Mich. : Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.