Resistance to Daptomycin in the Treatment of Methicillin Resistant Staphylococcus aureus Bacteremia
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Authors
Chase, Patrick
Issue Date
2007-04-27
Type
Language
en_US
Keywords
Alternative Title
Abstract
Staphylococcus aureus is an aerobic gram positive bacterium that can
cause harmful skin infections and bacteremia. Some strains of S.
aureus have become resistant to synthetic penicillin (Methicillin) and
therefore need to be treated with Daptomycin, a novel lipopeptide
antibiotic that was approved by the Food and Drug Administration
(FDA) for treatment of gram positive skin infections in 2003. Two
patients at St. John Hospital & Medical Center (Detroit, MI) were on
prolonged treatment of Daptomycin for S. aureus bacteremia and blood
cultures showed non-susceptibility to the drug. Both patients’ blood
cultures were shown to develop non-susceptibility to Daptomycin after 5
and 7 days of treatment.
Description
1 broadside : ill.
Citation
Publisher
Kalamazoo College