Nuclear Localization of Tobacco Etch Virus Proteins
Loading...
Authors
Leinicke, Andy
Issue Date
1991
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
The Tobacco Etch Virus (TEV), a member of the Potyvirus group of plant viruses, has a (+)
sense RNA strand which acts as mRNA inside a host plant cell. TEV RNA codes for a single
precursor polypeptide which is autolyticially cleaved into polyfunctional proteins. The nuclear
inclusion protein (a) is a replicative and proteolytic protein which accumulates in the nucleus via a
known nuclear localization signal (NLS) (Carrington, 1990b). Nuclear localization has been
extensively characterized in animal systems, but is largely ambiguous in plants. In this experiment, I
have assayed serial deletions from the Nand C termini of the NIa protein NLS for nuclear
localization. I have determined the location of the NLS more precisely on the Nla protein and
characterized the NLS more extensively.
Description
ii, 19 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.