The Reactions Of Methylenecyclopropylketones With Diorganolithium Cuprates
Szmuszkovicz, Jacqueline R.
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Methylenecyclopropanes have recently been the subject of several interesting mechanistic! and synthetic2 studies. Although its exocyclic double bond imposes additional strain on the three-membered ring,3 methylenecyclopropane (b.p. 11°C) is surprisingly stable. It is now available on a kilogram scale4 and can be stored in a cylinder for several years at room temperature without significant decomposition.5 It is interesting to note that some naturally occurring compounds (including hypoglycin A)6 contain this highly strained unit.