Molecularly Imprinted Polymers and Their Use in Electrochemistry
Molecularly imprinted polymers has been widely studied as synthetic replacements for natural antibodies. They have been shown to bind certain biologically active molecules with high rates of selectivity. This study focuses on developing these polymers in order to extend their use to an electrochemical realm. Preliminary studies focus on the development of a working polymer for biotin and its derivatives. When the polymer is found to accomplish reasonable capability to bind, based upon its binding capacity and selectivity in a competitive environment, it will be introduced to an electrochemical environment by means of a synthetically produced biotin derivative with a ferrocene electrochemical center. This study accomplishes the formation of a working polymer as well as an electrochemically active biotin compound.