JavaScript is disabled for your browser. Some features of this site may not work without it.
  • About K
  • Academics
  • Admission
  • Alumni Relations
  • Giving to K
  • News & Events
  • Student Life
  • HORNET HIVE
  • ATHLETICS
  • SITEMAP
  • WEBMAIL
    • Login
    View Item 
    •   CACHE Homepage
    • Academic Departments, Programs, and SIPs
    • Biology
    • Diebold Symposium Posters and Schedules
    • View Item
    •   CACHE Homepage
    • Academic Departments, Programs, and SIPs
    • Biology
    • Diebold Symposium Posters and Schedules
    • View Item

    Analysis of the HD and ACT domains of the E. coli signal-transducing Uridylyltransferase /Uridylyl-removing enzyme (UTase/UR)

    Thumbnail
    View/Open
    poster presentation (138.2Kb)
    Date
    2008
    Author
    Ouillete, Ryan Matthew
    Metadata
    Show full item record
    Abstract
    The uridylyl-transferase/uridylyl-removing (UTase/UR) enzyme is part of two important signaling cascade mechanisms that control cellular function in response to signals of carbon and nitrogen status (figure 1). The sequence of UTase/UR, from the gln D gene located on the glnALG operon in E. coli, encodes three domains that are highly conserved across a number of other proteins, namely the NT, HD, and ACT domains. The NT (nucleotidyltransferase) domain has been studied in great depth. However, little is known about the HD and ACT domains. One specific mutation, D105N, has been found to cause the loss of both activities of UTase/UR. In response, it has been suggested that the two catalytic activities of UTase/UR are located within the NT domain. In this experiment, mutations of highly conserved residues in the HD and ACT domains of UTase/UR were studied to determine effects on enzyme wild-type function. Understanding how these domains contribute to proper enzyme function in UTase/UR can offer insight about their role in other proteins in which they are present.
    URI
    http://hdl.handle.net/10920/4930
    Collections
    • Diebold Symposium Posters and Schedules [444]

    Browse

    All of CACHECommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV
    Logo

    Kalamazoo College
    1200 Academy Street
    Kalamazoo Michigan 49006-3295
    USA
    Info 269-337-7000
    Admission 1-800-253-3602

    About K
    Academics
    Admission
    Alumni Relations
    Giving to K
    News & Events
    Student Life
    Sitemap
    Map & Directions
    Contacts
    Directories
    Nondiscrimination Policy
    Consumer Information
    Official disclaimer
    Search this site


    Academic Calendars
    Apply
    Bookstore
    Crisis Response
    Employment
    Library
    Registrar
    DSpace Express is a service operated by 
    Atmire NV