Investigation of the Juvenile Hormone nuclear receptor as target forFMRFamide and SCP
Loading...
Authors
Bielang, Rebecca E.
Issue Date
2002-05-03
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
• Juvenile Hormone (JH) is a hormone found in insects. It
is crucial to their development in both larval and adult life
cycles.
• JH needs a nuclear receptor in order to act. Many
researchers have looked for this elusive and important
receptor without any successful results.
• Flies with apterous (AP) gene mutations have a
pleitotropic phenotype. They lack wings; more importantly,
they lack FMRFamide and SCP expression in thoracicventral
(Tv) neurons.
• The regulatory sequences that drive the Drosophila
FMRFamide gene expression to the Tv cells have been
shown to contain binding sites for AP.
• A previous study showed that increasing apterous
expression resulted in an increase of JH, which in turn
caused the FMRFa expression to be rescued.
Description
1 broadside : ill.
Citation
Publisher
Kalamazoo College