Serotonin Receptor Antagonist Has a Neuroprotective Effect in a C. elegans Neurodegenerative Model

dc.contributor.author	Harding, Madeline
dc.date.accessioned	2022-05-02T13:29:38Z
dc.date.available	2022-05-02T13:29:38Z
dc.date.issued	2022
dc.identifier.uri	https://cache.kzoo.edu/handle/10920/43565
dc.description	1 Broadside. 48"W x 36"H	en_US
dc.description.abstract	Neurodegenerative diseases are characterized by the progressive and abnormal death of neurons. Glutamate excitotoxicity is known to be a common mechanism leading to neuronal death in many neurodegenerative diseases. Antagonizing glutamate receptors with drugs such as MK-801 in vivo at high dosages causes damaging side effects, thus a new model for modulating extracellular glutamate is needed. Serotonin has been shown to regulate glutamate transmission. 5-HPEC is a serotonin receptor was investigated for its neuroprotective effects in Caenorhabditis elegans (C. elegans).	en_US
dc.description.sponsorship	Kalamazoo College. Department of Biology. Diebold Symposium, 2022	en_US
dc.format.mimetype	application/pdf
dc.language.iso	en_US	en_US
dc.publisher	Kalamazoo, Mich. : Kalamazoo College	en_US
dc.relation.ispartof	Kalamazoo College Diebold Symposium Presentation Collection	en
dc.rights	U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.	en
dc.title	Serotonin Receptor Antagonist Has a Neuroprotective Effect in a C. elegans Neurodegenerative Model	en_US
dc.type	Presentation	en_US

Diebold Symposium Posters and Schedules [479]
Poster and oral presentations by senior biology majors that include the results of their Senior Integrated Projects (SIPs) at the Diebold Symposium. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.