Tracking Insecticidal Activity of Peptide-based Insecticide Across Insect Assays
Abstract
Insect control as well as insecticide resistance and management is essential to
maintain and expand the agricultural industry. As such, the need for effective
and safe insecticides is increasingly important as cases of insecticide
resistance to chemical insecticides continue to rise.1 Vestaron is an emerging
leader in the biopesticide industry, focusing on developing safe and effective
products.2 Their first product on the market, Spear, is a novel peptide-based
insecticide. Most recently Vestaron is developing a new product code-named
7304 as a Lepidoptera targeting insecticide. In this study I analyze the
wildtype strain of peptide along with three mutants (Table I) across insect
(Figure 1) injection and feeding assays to elucidate how key mutations to the
original peptide increased the stability of 7304 in Lepidoptera guts.
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