Search for Significant Biomarkers Associated with Acute Kidney Injury (AKI) in Patients Enrolled into Phase III Clinical Trial

Abstract

Cardiac induced AKI is the rapid degeneration of kidney function within days or weeks of cardiac surgery and consequently leads to a buildup of waste products, fluids, and electrolyte imbalances. Among patients who undergo cardiac surgery, up to 30% will develop AKI (Rosner & Okusa, 2006). Currently there are no effective therapies for the prevention or treatment of AKI.