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Inhibition of Avian Leukosis Virus Replication by RNA interference Using miRNAs
(Kalamazoo College, 2007-04-27)
To use retroviral-based miRNA vectors to repress translation of SU(B), a viral envelope protein necessary for reproduction of ALV-B - To develop effective retroviral miRNA vectors transcribed from an RNA-polymerase II promoter
Inhibition of avian leukosis virus replication by RNA interference using miRNAs
(Kalamazoo College, 2007)
Avian leukosis virus (ALV) is a tumor-inducing retrovirus that threatens agricultural chicken populations. Though no effective vaccine currently exists, RNA interference (RNAi) is a developing tool that can be effective ...