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Generation of Stable Cell Lines Expressing Notch and Presenilin: Insights into the Function of Presenilin in Notch Signaling and Alzheimer's Disease
(Kalamazoo College, 2000)
Familial early-onset Alzheimer's disease (FAD) affects approximately 10% of all cases of Alzheimer's disease. F AD is associated with dementia and neurofibrillary tangles, but its most distinctive feature is the deposition ...