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Now showing items 1-10 of 27
Diebold Symposium Schedule 2001
(Kalamazoo, Mich. : Kalamazoo College, 2001)
Schedule for the Diebold Symposium held Thursday, April 26, to Saturday, April 28, 2001, on the campus of Kalamazoo College. "Coping With Microbes: A Genetic and Genomic View of How Plants Do It" was the Keynote Address ...
Evaluation of Zolpidem (Ambien®) as a Selective Benzodiazepine Agonist in a Primate Model
(Kalamazoo College, 2001)
Anxiety and insomnia are two of the most prevalent behavioral disorders in
society. The molecular basis of these illnesses is not well known, however two classes of drugs are effective in the treatment of these disorders: ...
Evaluation of an ER Export Signal on an Amyloid Precursor Protein Mutant Associated with Alzheimer's Disease
(Kalamazoo College, 2001)
Alzheimer's Disease (AD) is one of the most common human neurodegenerative
disorders. Most early-onset familial AD forms (FADs) have one of four genes, which is the amyloid precursor protein (APP). AmyloId plaques In the ...
Phylogenetics of Three Populations of the Tasmanian Giant Lobster (Astacopsis Gouldi)
(Kalamazoo College, 2001)
The Tasmanian giant lobster, Astacopsis gouldi is an endangered species of
crayfish isolated to the north and northwestern regions of Tasmania. Over the past ten
years, Australia has been undergoing one of its most ...
An Examination of Variation in Common Chimpanzee Pant-Hoot Vocalizations for Evidence of Vocal Learning and Developmental Instability
(Kalamazoo College, 2001)
The distinctive long distance pant-hoot vocalizations of male common chimpanzees, Pan troglodytes, were studied in a captive colony at the Yerkes Regional Primate Research Center in Atlanta, GA to examine inter-population ...
A Study of Cytochrome P450's Level and Method of Response to the Common Environmental Compound Ethylbenzene
(Kalamazoo College, 2001)
Cytochrome P450 is a super family of enzymes that metabolize a wide variety of
endogenous and exogenous compounds. These enzymes are involved in the bioactivation of xenobiotics and drug metabolism, which may cause P450 ...
The Discriminative Stimulus Properties of the kappa Opioid, U-50,488H in Rats
(Kalamazoo College, 2001)
The discriminative stimulus effects of the K-opioid antagonist, U-50,488H, were
examined in this study. During training sessions, rats were conditioned to discriminate
U-50, 488H versus vehicle (saline). Five male rats ...
Characterization of SEQ-9 an Orphan G protein-Coupled Receptor
(Kalamazoo College, 2001)
Current research in pharmaceuticals is primarily focused on cell signaling pathways.
G-proteins (GTP binding proteins) are a particularly favorite drug target because of their
ubiquitous expression and the vast number ...
Nociceptin-Induced Antinatriuresis is Affected by the Renin-Angiotensin-Aldosterone System
(Kalamazoo College, 2001)
Nociceptin (Orphanin FQ) is an endogenous peptide whose structure is similar to
that of endogenous opioid peptides (Meunier, et aI., 1995; Rienscheid, et al., 1995).
Nociceptin has generated interest because of its ...
Chronic Treatment of LAAM and Buprenorphine in Heroin and Buprenorphine Discriminating Pigeons
(Kalamazoo College, 2001)
As abuse of opioids, such as heroin, are growing concerns; even more important
are therapies for drug cessation. In human patients there has been evidence that a therapy called "substitution therapy" has helped individuals ...
