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Structural Characterization of Clostridium difficile TcdR, a Sigma Factor that Controls Bacterial Toxin Production
(Kalamazoo College, 2019)
Clostridium difficile infections in the colon cause severe diarrhea and pseudomembranous colitis, with pathology stemming from two secreted bacterial toxins, TcdA and TcdB. With C. difficile infection rates on the rise in ...