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Poster and oral presentations by senior biology majors that include the results of their Senior Individualized Projects (SIPs) at the Diebold Symposium.
Type 2 diabetes is characterized by inadequate pancreatic beta-cell function and insulin resistance. Insufficient nutrition during critical time windows of fetal development may predispose offspring to type 2 diabetes. ...
Models have been used to study transmission dynamics for over 100 years, earlier than even the Ross model in the early 1900's. The modeling of multihost, vector-borne pathogens such as West Nile virus and Lyme disease has ...
Insulin resistance is a known precursor to metabolic syndrome, cardiovascular disease and type II diabetes. Our lab has previously demonstrated that consumption of a strawberry treatment beverage with a high fat/carbohydrate ...
Neurotrophic factors are crucial to the development, function, and survival of neurons. Glial cell line-derived neurotrophic factor (GDNF) is considered the most potent survival factor for motor neurons. GDNF functions as ...
The accumulation of unfolded/misfolded proteins in the endoplasmic reticulum is a condition known as endoplasmic reticulum stress (ER stress). This condition is combated by a series of signal transduction pathways collectively ...
Heart disease is a common affliction that affects the quality of life and is the leading cause of death in the US. Familial hypertrophic cardiomyopathy (FHC) is caused by several mutations, some of which occur in α-tropomyosin. ...
RNA is widely known to be an integral part of transcription and gene regulation. The RNA world hypothesis states that RNA is the precursor to life and biological processes as we know them today, but in order for this to ...
The conserved process of autophagy is a degradation process vital to cellular function. The initial step of autophagy occurs through the formation of the preautophagosomal structure (PAS). Although this step is central to ...
Objective: To evaluate the relevance of traditional predictors of technical success of percutaneous revascularization of chronic total occlusions (CTOs) in the superficial femoral artery (SFA) with the aid of reentry devices ...
Metamorphosis in tunicates marks the shift from a motile larva to a sessile adult. The timing of genes expressed during metamorphosis can be crucial to the development of a normal adult phenotype. One particular gene, ...
As the threat of coronary artery disease (CAD) rises through the decades, developing a nearly painless, but efficient, method of scanning for the disease becomes imperative. This proposal was developed to outline, ...
Contrast induced nephropathy (CIN) is a clinical condition often exhibited by patients undergoing cardiovascular procedures requiring the visualization of blood vessels. To enhance the visibility of blood vessels, radiocontrast ...
Nuclear receptors (NRs) are eukaryotic transcription factors that regulate many physiological processes including growth, inflammation, and circadian rhythms. Rev-erbβ is a NR that regulates genes involved with metabolism ...
Humans and wildlife are exposed to many thyroid disrupting chemicals which can interfere with the thyroid hormone system. Thyroid hormones are critical to the development of the brain and auditory system. Thus, thyroid ...
Jahant-Miller, Chelsea J.(Kalamazoo College, 2014)
This study has important agricultural implications on reducing incidence of leaf damage done by folivorous insects. Increasing foliar fiber content in some crops could be an efficient method for non-chemical pest control. ...
Cladophora glomerata, a filamentous green alga native to the Laurentian Great Lakes, has become a nuisance to the shorelines of the lakes. Productivity of this alga has increased in the past twenty years with the introduction ...
Precocial birds develop from ectothermy to endothermy during the final days of incubation and the first 24 hours after hatching. Onset of endothermy and the ability to thermoregulate is concurrent with ductus arteriosus ...
Inflammation is a protective response to pathogens, but can have dangerous immunopathological consequences including shock. One mediator of inflammation is Toll-like receptor 4 (TLR4), which binds Pathogen-Associated-Mol ...
The pregnane X receptor (PXR) is a nuclear receptor transcription factor that regulates transcription of genes for proteins involved in xenobiotic and endogenous chemical disposition and metabolism, including phase I/II ...
Cervical contusion trauma is the most common form of spinal cord injury (SCI) from which 10% of individuals regain motor function. Pathology of SCI often leads to full quadriplegia or paraplegia due to secondary injury ...