The Effect of Cue Familiarity on Flavor-mediated Augmentation
Jensen, Clare L.
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In a typical A+/AX+ experimental design, the CS A preconditioned with the US will usually create a heightened aversion to the target CS X, a phenomenon known as augmentation. In latent inhibition, pre-exposure to a CS that make it familiar will reduce the learning when that same CS is subsequently followed by the US. In this study, the two phenomena are combined in order to analyze the formation of within-compound associations as they relate to the theoretical background and the practical background of behavioral interventions used to treat anticipatory nausea (AN) in chemotherapy patients. Rats are given 0, 1, or 4 pre-exposures to the target CS X before undergoing either a compound conditioning procedure as the control, or an augmentation procedure as the experimental condition. The strength of aversion to the CS X is tested to determine if familiarity can weaken the within-compound association, thus preventing augmentation. Experiment 1 shows that pre-exposing the taste SAC cannot prevent augmentation by the odor AL. Experiment 2 shows that pre-exposing the odor AL cannot prevent augmentation by the taste SAC. Therefore, the scapegoat technique that utilizes the same process cannot be used more than once, because the within-compound association that can cause augmentation is still formed.