Cloning and Expression of the Zebrafish Gene; Setd8
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Authors
Thompson, Shatia
Issue Date
2012
Type
Presentation
Language
en_US
Keywords
Alternative Title
Abstract
Squamous cell carcinoma (SCC) is a malignant tumor of the
squamous epithelium and one of the six most common cancers
worldwide. Decreased Ikk1 activity is commonly associated with
SCC. Ikk1 is a member of the intracellular signal transduction
enzyme family and has been identified as a major regulator of
differentiation in mammalian skin. The poky mutation stems from a
mutation in the zebrafish homolog of Ikk1, and results in almost an
identical phenotype as the loss of IKK1 in mammals. Poky mutants
are deficient in EVL differentiation and exhibit defective epiboly
progression.
Description
1 Broadside. Original created in Microsoft PowerPoint. 48"W x 36"H
Citation
Publisher
Kalamazoo, Mich. : Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.