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dc.contributor.authorJanes, Zachary
dc.description1 Broadside. Original created in Microsoft PowerPoint. 48"W x 36"Hen_US
dc.description.abstractSyntheQc chemicals with biological acQvity, many of which can adversely affect the health of marine organisms, are present in the world’s oceans. Polychlorinated biphenyls (PCBs) have been linked to endocrine disrupQon1, developmental toxicity and neurotoxicity2. The killifish populaQon of New Bedford Harbor (NBH), MA has evolved mechanisms to deal with PCBs and has remained reproducQvely prolific3. Zebrafish are a good lab model to test the sole effects of maternal PCB treatment, thus eliminaQng other environmental factors that may affect CYP transcript expression within the killifish populaQon. Cytochrome P450s (CYPs), heme-­‐containing proteins that funcQon in both endogenous and exogenous chemical metabolism, aid in the metabolism of PCBs. Li\le is known as to whether CYPs contribute to embryonic development or serve a funcQon in the developing xenobioQc response of the embryo.en_US
dc.description.sponsorshipKalamazoo College. Department of Biology. Diebold Symposium, 2012en_US
dc.publisherKalamazoo, Mich. : Kalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Diebold Symposium Presentation Collectionen
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.en
dc.titleExposure to Toxic Chemicals Affects Cytochrome P450 Transcript Expression in Early Development in Two Teleost Fish, Killifish and Zebrafishen_US

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  • Diebold Symposium Posters and Schedules [320]
    Poster and oral presentations by senior biology majors that include the results of their Senior Individualized Projects (SIPs) at the Diebold Symposium. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

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