The Short-Term Effects of Strawberries on Postprandial Insulin Responses

Abstract

• The postprandial state is characterized by increased oxidative stress and inflammation from metabolism and storage of macronutrients. • Oxidative stress alters the redox balance of cells, decreasing insulin efficiency and the body’s ability to restore homeostatic balance, and over time, contributes to insulin resistance. • Insulin resistance is the decreased efficiency of insulin at regulating downstream pathways and is a precursor to cardiovascular disease, atherosclerosis, obesity and type II diabetes. • Phytochemicals, such as those in strawberries, consistently lower markers of oxidative stress and inflammation when consumed meals typical of the Standard American Diet, attenuating the development and effects of insulin resistance. • Thus, this pilot study investigated the effects of strawberries (in the form of a milk-based strawberry drink), on human plasma concentrations of insulin, glucose, and triglycerides after a HFMC meal.