Show simple item record

dc.contributor.advisorBatsell, W. Robert, 1963-
dc.contributor.advisorBamford, Nigel M.
dc.contributor.authorErbe, Jeff K.
dc.descriptionv, 30 p.en_US
dc.description.abstractDetermining the mechanism by which methamphetamine effects striatal functioning is an important goal in attaining further insight for the neuronal effects of methamphetamine and exact processes by which neurotoxicity occurs. The present experiment is a preliminary study that used a terminal deoxynucleotidyl transferase-mediate dUTP nick end labeling [TUNEL] kit to identify cell death, due to methamphetamine, in three distinct regions of mouse striatum This was observed in both adult and developing mice pups. Pregnant female mice were injected with either 20-mg/kg or 30-mg/kg body weight amounts of methamphetamine hydrochloride for I 0 days during pregnancy and the brains tissue samples were taken from their pups at days PIO (10 days after birth), P30, and then as adults. Results showed most cell death occurred in rostral striatum. The P30 mice revealed significantly more cell death than P10 and adult mice.en_US
dc.description.sponsorshipDepartment of Neurology. University of Washington. Seattle, Washington.
dc.publisherKalamazoo, Mich. : Kalamazoo College.en_US
dc.relation.ispartofKalamazoo College Anthropology and Sociology Senior Individualized Projects Collection
dc.relation.ispartofseriesSenior Individualized Projects. Anthropology and Sociology.;
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.
dc.titleEffects of Methamphetamine in the Motor Striatum of Miceen_US
KCollege.Access.ContactIf you are not a current Kalamazoo College student, faculty, or staff member, email to request access to this thesis.

Files in this item


This item appears in the following Collection(s)

  • Anthropology and Sociology Senior Individualized Projects [652]
    This collection includes Senior Individualized Projects (SIP's) completed in the Anthropology and Sociology Department. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

Show simple item record