An Examination of the Intensity of Laser Light as a Function of Depth in Dog Tiesue with Consideration Given to Absorption and Scattering Characteristics
Jacobs, Randall Scott
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This project involved an examination of the change in intensity of laser light as a function of depth in dog muscle tissue. An attempt was made to find some way to characterize the behavior of the light intensity consistently, with the hope of revealing something about the absorption and scattering characteristics of tissue. The results pointed to the possibility that perhaps the light intensity can be described by two exponential functions in tissue. The data showed that the light seemed to follow one exponential relationship and at a certain depth in the tissue it began to behave by another exponential function. This data raised a number of questions and perhaps can be a stimulus for further work on this subject. The motivation for this work is the use of a laser surgical procedure for terminally ill cancer patients called photoradiation therapy. Photoradiation therapy makes use of a chemical called hemataporphoryrin which selectively concentrates in cancerous tissue and if activated by the appropriate wavelength of laser light destroys the malignant cells. By finding how laser light intensity changes as a function of depth in tissue one may then know how much light to use in treatment of a patient by photoradiation therapy.