A Kinetic Study of Lymphocyte Surface Antigens Using Flow Cytometry
Bailey, Lisa G.
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One of the major steps toward treating disease is the discovery of the pathological element of the cell. Minute cell changes occurring in cell surface antigens can be the clue to detecting, for example, cancer or AIDS. Flow cytometry is a method used by pathology laboratories to rapidly screen a population of cells for such changes. Flow Cytometry involves the use of fluorescent dyes to mark specific cellular components. These dyes are quantitative and specific in that the amount of dye uptake is directly proportional to the amount of a particular cellular component. This study used Flow Cytometry to analyze the behavior of human lymphocyte surface antigens over time in differing environments.