The Effects of Increased Physiological Severity of Surgical Intensive Care Patients on Protein Loss through Sputum, Bile, Lung Blood and Respired Water
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Protein loss was analyzed in sputum (collected from Naso-Gastric cavity), respired water, chest tubes and bile (collected from the liver) from 14 Surgical Intensive care patients at the University of Michigan Hospitals. The patients in the study were afflicted with various respiratory dysfunctions and liver cirrhosis. The aim of the study was to determine a relationship between severity score of the patient and protein lost through these various viscera. The severity score of the patients was detennined using the APACHE IT (a severity of disease classification system). The specimens of sputum, lung blood, bile and respired water were analyzed using a pyro-chemiluminescence technique; a variation of the Kjeldahl technique. It was concluded that only protein loss through the lung viscera showed a correlation to the increasing severity score of the patients. Protein losses through bile, sputum, and respired water showed no correlation to the increase in the patients severity score.