Relationship Between Digoxin and Kidney Function
Sonke, Craig Richard
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Digoxin, a therapeutic medication ramifying the adverse effects of congestive heart failure, is transported to the heart via the circulatory system. Once in the bloodstream, some digoxin associated with heart muscle causing a positive inotropic action upon the myocardial tissue, while much is passed through the kidneys and rapidly excreted. This study involves the relationship between a patient's kidney function, exposed by values of blood urea nitrogen and creatinine, and his blood level of digoxin with contention that as function decreases, drug level increases. The relationship is supported by the data and may simplify the physicians judgment in determining possible digoxin toxicity.