A Morphological and Histological Investigation into the Reproductive Anatomy of C57BL/6J - X/Y^h Hermaphroditic Mice
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Authors
Morrow, Katharine
Issue Date
1980
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
External and internal reproductive anatomy was examined in 307 C57BL/6J mice
carrying a Y-linked mutation known to produce true hermaphroditism. Histological
preparations were made from gonads of a representative sample of 64 hermaphrodites,
which expressed a wide range of variation in their internal reproductive organs.
Analysis revealed that 98% of these gonads were ovotestes and 2% were ovaries; no
testes without ovarian tissue were found. In addition, a direct correlation was
found between ovotestis development and the phenotypic development of the reproductive anatomy.
A preliminary investigation of gonads from 15 day old C57BL/6J fetuses carrying
this mutation was done to ascertain the early development of the hermaphroditic
gonad. Results are discussed in terms of their implications for genetic mechanisms
of sex differentiation.
Description
i, 23 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.