The Effects of Cold Exposure on Oxygen Consumption in Wild Mus Musculus, Peromyscus Leucopus, and 25 Crossbred Strains of Laboratory Mice
Tiefenthal, Carol A.
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A cold exposure study was done as part of a larger longevity study on mice. This study involved twenty-five cross bred strains of laboratory mice plus Mus musculus, the house mouse, and Peromyscus leucopus, the white-footed mouse. The hypothesis was that lifespan decreases as metabolic rate (or oxygen consumption) increases. It was found that by artificially stimulating the crossbred strains, an overall decrease in lifespan resulted. Because or insufficient data for metabolism measurements in older aged Mus and Peromyscus, only the following general conclusions can be made at this time. Mus showed no great decrease in lifespan, although its metabolic rate was increased. Peromyscus showed both a reduction of lifespan and an increase in metabolic rate.