The effect of changing transmural arterial pressure gradients on pressure pulse wave propagation velocity in the lower limbs of healthy human subjects and its relevance to the atherosclerotic patient.
Merigian, Kevin S.
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In recent years Gosling and king of Guys Hospital in London, England have devised a new method for assessing the severity of arterial occlusive disease in patients. The method consists of transducing simultaneously the blood velocity at two sites of arterial network using two simple continuous wave doppler ultrasound flowmeters. The test has been employed in England and seems to be successful in exposing arterial occlusive disease. However, the test needs to be proven effective for patients in the U.S.A. This study was devised to do that task. Data were gathered from changing the blood pressure gradients in the lower limbs. This was done by changing the position of the subject, i.e., the position of the resting body rotated through 180 degrees. The transit times and pulse pressure propagation wave velocity were compared to the findings of Gosling and King. From the data gathered and analyzed, it appears that the tests may soon be employed in the U.S.A.
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