The Quantitative Parameterization of the Platelet Aggregation Curve
Morrison, Thomas A.
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The purpose of this project was to obtain some general knowledge of the platelet, and. to devise a quantitative means of analyzing two types of platelet aggregation curves: 1. the monophasic (rat platelet) curve, and 2. the biphasic (human platelet) curve. This was achieved. by the in' vitro aggregation of platelets using various concentrations of epinephrine and noting the effect on the various parameters. It was found that increasing concentrations of epinephrine caused an inhibition of platelet aggregation in both the rat and the human.