Interferon Induction by a Highly Substituted Pyrimidine Base in Mouse Thymus Cell Suspensions
Andrews, John C.
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This study characterized a new interferon inducer-cell system involving a highly substituted pyrimidine base inducer and mouse thymus cell suspensions. The system found to be optimal for this study consisted of: cell concentration - 3.0 x 108 cells/ml; drug concentration - 2 mg/ml; incubation time - 10-14 hours; temperature - 37°C; producing an interferon titer of approximately 400 units.