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dc.contributor.advisorDay, Charles E.
dc.contributor.authorThomson, Stephen P.
dc.descriptionv, 22 p.en_US
dc.description.abstractNo major research efforts have been directed toward the development of animal models which parallel the hyperlipoproteinemic states of man. The development of such an animal model was recommended by the Task Force on Arteriosclerosis, of the National Heart and Lung Institute of the National Institute of Health. Alexander and Day (1973) have shown that both the snake and opossum are good candidates for the model based on the electrophoretic mobilities of their lipoproteins. The present study characterizes tile lipoproteins of these animals in greater detail and examines two other models, one using a chemical compound (U-21,74) to induce a hyperlipoproteinem ic state in white rats, the other using carbohydrate,_ to induce hyperlipoproteinemia in the BHE strain. of rats. Both the snake and the opossum were found to have serum lipoproteins whose compositions are quite similar to human lipoproteins.en_US
dc.publisherKalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Biology Senior Individualized Projects Collection
dc.relation.ispartofseriesSenior Individualized Projects. Biology;
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.
dc.titleThe Green Snake, Opossum and Rat as Animal Models of the Hyperlipoproteinemic State of Manen_US

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  • Biology Senior Individualized Projects [1489]
    This collection includes Senior Individualized Projects (SIP's) completed in the Biology Department. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

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