Show simple item record

dc.contributor.advisorOlexia, Paul D., 1939-
dc.contributor.advisorDimino, Michael J.
dc.contributor.authorLabbe, Stephen D.
dc.descriptionvi, 33 p.en_US
dc.description.abstractMitochondria were isolated from the ovaries of mature rats. Polarographic techniques were used to measure state III resp1ration, State IV respiration, Respiratory Control Ratios (RCR) ,and ADP:O ratios. Addition of Luteinizing Hormone (LH,5O ug) in vitro had no effects on any parameter of ovarian or liver (control) mitochondrial respiration. The effects of 3',5'-Adenosine Monophosphate (c-AMP) and Adenosine Monophosphate (AMP) on ovarian mitochondrial respiration were also studied. Cyclic AMP (0.3 mM) caused significant increases in state III (p<0.00l) and state IV (p<0.0l) respiration, while not affecting RGR or ADP:O ratios. Liver mitochondria, used as a control, were not affected. AMP (0.3 mM) had similar effects as c-AMP. Various methods of isolating ovarian mitochondria were attempted in order to maximize mitochondrial yields while minimizing losses in viability.en_US
dc.publisherKalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Biology Senior Individualized Projects Collection
dc.relation.ispartofseriesSenior Individualized Projects. Biology;
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.
dc.titleThe In Vitro Effects of Luteinizing Hormone on Rat Ovarian Mitochondriaen_US

Files in this item


This item appears in the following Collection(s)

  • Biology Senior Individualized Projects [1489]
    This collection includes Senior Individualized Projects (SIP's) completed in the Biology Department. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

Show simple item record