The Nomenclature, Mechanism and Function of Enzymes
Langford, Joseph W.
MetadataShow full item record
This paper is divided into three parts. The first part deals with terminology and must be presented before enzymes can be discussed adequately. The second and most extensive part deals with the mechanism of enzyme action. A general mechanism for all enzymes 1s postulated on the basis of experimental observation. Principles of thermodynamics, important to the concept of enzyme action, are used to explain the fact that enzymes lessen the energy requirement of a chemical reaction. The reasons why an enzyme's action is affected by the concentrations of the enzyme and the reactant are given. Chemical mechanisms are included and show how enzymes, metal ions, and co-enzymes help the atoms of a reactant to move in a way which allows a reaction to occur. A section on oxidation-reduction reactions gives some basic properties or metabolic systems. The third part of the paper covers some of the different types of reactions which are catalyzed by enzymes.