Browsing Academic Departments, Programs, and SIPs by Author "Nagler, Brendan"

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Effect of a Stem I Substitution on the Self-Cleavage Rate of a Hammerhead Ribozyme

Nagler, Brendan (Kalamazoo, Mich. : Kalamazoo College, 2013)

Hammerhead ribozymes have been the focus of much research including therapeutics against cancer and viral infection. Hammerhead ribozymes are small self-cleaving RNAs characterized by a hammerhead motif – three short helices ...
Effect of a Stem I Substitution on the Self-Cleavage Rate of a Hammerhead Ribozyme

Nagler, Brendan (Kalamazoo College, 2012)

RNA is a significant fixture in important biological processes. It serves a diverse array of functions, such as a catalyst in chemical reactions and a role in gene regulation. RNAs that catalyze chemical reactions are ...