Extraction of 4,5',8 - Trimethylpsoralen from the Skin of Hooded Rats
Smith, Frederic Earle
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The purpose of this investigation was to determine if a highly active furocoumarin 10, 4, 5', 8-trimethylpsoralen (I) could be applied topically to the skin of a laboratory rat, extracted from that tissue, and identified on a thin layer chromatogram by means of its flouresccnce. Hooded rats were chosen in an effort to induce a tanning response in a laboratory animal which had pigment forming capability.