A Synthesis to Incorporate C13 At C(21) of Methyl (20S 22E)-3ß-Acetoxychola-5,22-Dienate
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Authors
Capes, Hubbard C., Jr.
Issue Date
1979
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
The main goal of this project was to synthesize 1 and 2
and incorporate a c13 atom in the molecule at the C{21) position.
With a C13 atom at this position in the molecule, distinct
signals could be observed in the C-NMR spectra and differences
observed between location of peaks corresponding to the
20b-H and 20a-H sterols, 1 and 2. The result of this c13 labeling
is to add C13-NMR to the other methods already in use
to differentiate between other steroids epimeric at C(20).
Description
16 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.