Studies Toward the Synthesis of Diethyl 3,5-Dinitropyrrole-2,4-Dicarboxylate
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The synthesis of diethyl 3,5-dinitropyrrole-2,4-dicarboxylate was attempted by four synthetic routes (Schemes I to IV). Reactions studied included the halogenation and nitration of some substituted pyrroles. Nitration was accomplished either directly or by displacement of acetyl- or halo-groups present in the pyrrole ring. Halogenated pyrroles were also found to be subject to nucleophilic displacement by cyanide ion. While several new pyrroles were prepared, progress made thus far in the investigation of the reaction schemes has not afforded the diethyl 3,5-dinitropyrrole-2,4-dicarboxylate.