The Synthesis of Isomeric Thiazole Amino Acids
Wagner, John R., Jr.
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This thesis is an extension of the work commenced in the cancer research unit of the Upjohn Company concerning the synthesis and characterization of Dolastatin 3. The investigation of synthetic pathways for isomeric glycine thiazole amino acids, as well as a comparison of these synthetic products to the thiazole amino acid moieties found in Dolastatin 3, will be described.