Purification and Characterization of a Phenylamine Isolated from Physarum Polycephalum Shortly before Mitosis
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Authors
Mernitz, Janice Lynn Koltko
Issue Date
1968
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
Mitosis is a highly complex, dynamic system about which relatively little is known. Swann' s review best
summarizes the voluminous experimental data and trends of thought
that have been established and that are being further studied
today. The most complete morphologioal account available on
mitosis is given by Mazia. An integrated biochemical
description of the mitotio process, although not yet available,
is very desirable.
Physarum polycephalum is an ideal experimental Subject
for mitotio studies; it is a large multi-nucleate plasmodium
in which the nuclei divide synchronously. Cell
division does not complicate a study of the intranuclear and
cytoplasmio mitotio events. Mitotio events are amplified as
the nuolei proceed together through the mitotic stages. In
previous work, now in press, an unknown substanoe(s) was
found in Physarum polycephalum which appeared shortly before
mitosis and disappeared before prophase. This thesis reports
on the isolation, purification, and characterization of this
oompound(s).
Description
ii, 30 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.