The Kinetics of Antibody Fixation to Lymphocytes

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Authors
Kooistra, Jon Brent
Issue Date
1968
Type
Thesis
Language
en_US
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Abstract
The purpose of this research was to provide accurate measurements of the primary binding of both normal gamma globulin and ALS preparations. to viable lymphocytes. In addition, the kinetics of this antigen-antibody reaction were investigated. Using 125 I-labeled antibody preparations, association, dissociation and equilibrium constants of the reaction of antibody with lymphocytes were determined. In addition, an equilibrium dialysis technique was developed in order to provide a direct measurement of an association constant for the formation of the antigen-antibody complex.
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24 p.
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Kalamazoo College
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U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder.
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