The Role of Aspartate in Retarding Fatigue in the Neuromuscular Level
Abstract
The purpose of this investigation was to study the
effect of aspartate in retarding fatigue at the neuro-muscular level. Various studies have been reported in
which aspartate has been administered. Laborit, et. al.
found that the K salt of aspartate reduced fatigue at
this level. They postulated that "aspartic acid which
functions in an intermediate position in the Krebs cycle
should provide a suitable substrate for the increase of
metabolic efficiency or delay of metabolic exhaustion."
Aspartate was administered orally to rats. They were then
put in a vat to swim until fatigue set in. With honors.