The Presence of t-RNA trp in Greene Hamster Melanoma Virus and its Use as a Primer for DNA Synthesis by RNA Dependent DNA Polymerase
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Authors
Theall, Gary
Issue Date
1976
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
Greene Hamster Melanoma Virus is also a RNA tumor virus. It is although a mammalian virus, not avian. However, due to the great similarities of the two systems, it was felt that t-RNA trp may also be a primer of DNA synthesis in the mammalian system. We were able to show through 32p labeling of the viral RNA and amino acylation of the RNA that there is trp-tRNA in the viral particle. This finding should allow us to show that this t-RNA will bind specifically to reverse transcriptase and that without the t-RNA DNA synthesis will not take place.
Description
iv, 29 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.