Show simple item record

dc.contributor.advisorMorton, D.R.
dc.contributor.authorHobbs, Steven J.
dc.date.accessioned2010-05-01T23:44:14Z
dc.date.available2010-05-01T23:44:14Z
dc.date.issued1976
dc.identifier.urihttp://hdl.handle.net/10920/14782
dc.descriptioniv, 101 p.en_US
dc.description.abstract2-Phenyl-l,3,2-dithioborolan and 2-chloro- 1,3,2-dithioborolan were investigated as possible reagents for the formation of cyclic thioketals and thioacetals in steriodal mono,di and triketones of the androstane and pregnane series, aryl aldehydes, alkyl and aryl ketones. Selective formation of the cyclic ethylene thioketal at position 3 (in yields greater than 75%) in steriodal 3,17 dione, 3,20 dione, 3,11,20 trione systems and high yields of the cyclic thioketals of the aryl aldehydes, alkyl ketones tested, was observed for 2-Phenyl-l,3,2-dithioborolan. 2-Phenyl-l,3,2-dithioborolan formed the cyclic ethylene thioketals of aryl katones in high yield, whereas 2-Phenyl-l,3,2-dithioborolan was quite unreactive. 2-Phenyl-l,3,2-dithioborolan also appeared much more reactive towards the carbonyl function than 2-Phenyl-l,3,2-dithioborolan. The results of preliminary solvent studies for 2-Phenyl-l,3,2-dithioborolan are presented.en_US
dc.description.sponsorshipUpjohn Company, Kalamazoo, MI
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.publisherKalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Chemistry Senior Individualized Projects Collection
dc.relation.ispartofseriesSenior Individualized Projects. Chemistry.;
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.
dc.titleThe Facile Preparation of Cyclic Ethylene Thioketals and Thioacetals with 2-Phenyl and 2-Chloro-1, 3, 2-Dithioborolansen_US
dc.typeThesisen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

  • Chemistry Senior Individualized Projects [889]
    This collection includes Senior Individualized Projects (SIP's) completed in the Chemistry Department. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

Show simple item record