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    The Effect of Adriamycin on Respiratory Control in Rat Heart Mitochondria

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    AnnWergelesChemSIP.pdf (8.371Mb)
    Date
    1975
    Author
    Wergeles, Ann
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    Abstract
    The purpose of this experiment was to monitor the oxidative phosphorylation of preparations of intact mitochondria from heart tissue of both adriamycin-treated and control rats. It was hoped that a link could be made between the cardiotoxic effect of the drug and altered levels of oxidative phosphorylation. If a change in ADP :O ratios was found an attempt would be made to see where adriamycin had its effect on the mechanism of oxidative phosphorylation using various substrates.
    URI
    http://hdl.handle.net/10920/14526
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