The Effect of Adriamycin on Respiratory Control in Rat Heart Mitochondria

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Authors
Wergeles, Ann
Issue Date
1975
Type
Thesis
Language
en_US
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Abstract
The purpose of this experiment was to monitor the oxidative phosphorylation of preparations of intact mitochondria from heart tissue of both adriamycin-treated and control rats. It was hoped that a link could be made between the cardiotoxic effect of the drug and altered levels of oxidative phosphorylation. If a change in ADP :O ratios was found an attempt would be made to see where adriamycin had its effect on the mechanism of oxidative phosphorylation using various substrates.
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iii, 27 p.
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Kalamazoo College
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U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.
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