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dc.contributor.advisorCounsell, Raymond E.
dc.contributor.advisorBrueggemeier, Robert W.
dc.contributor.authorFloyd, E. Elizabeth
dc.descriptionvi, 45 p.en_US
dc.description.abstractThe author participated in the doctoral dissertation research of Robert W. Bruggemeier at the University of Michigan, with three specific goals: (1) to set up a relatively simple enzymatic assay procedure designed to measure the conversion of 14C-androstenedione to radiolabeled estrogens; (2) to establish apparent KM and VMAX values for the enzyme-substrate system; (3) utilizing the enzyme assay, to test previously synthesized compounds for in vitro inhibition of estrogen production in an attempt to further elucidate the structural requirements for inhibition of the in vitro conversion of androgens to estrogens.en_US
dc.description.sponsorshipGraduate Program in Medicinal Chemistry, University of Michigan, Ann Arbor, MI
dc.description.sponsorshipDepartments of Medicinal Chemistry and Pharmacology, University of Michigan, Ann Arbor, MI
dc.publisherKalamazoo Collegeen_US
dc.relation.ispartofKalamazoo College Chemistry Senior Individualized Projects Collection
dc.relation.ispartofseriesSenior Individualized Projects. Chemistry.;
dc.rightsU.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.
dc.titleStudies of the In Vitro Conversion of Androstenedione to Estrogens by Human Placental Microsomesen_US

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  • Chemistry Senior Individualized Projects [889]
    This collection includes Senior Individualized Projects (SIP's) completed in the Chemistry Department. Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff.

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